Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MYOC | Q99972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768979 | 0.93 | HTT (0.58) | HTTPOLBKMT2AMEN1MAPT | |
| SCHEMBL11766345 | 0.89 | KMT2A (0.56) | HTTPOLBKMT2AMEN1MAPT | |
| SCHEMBL11766882 | 0.87 | KMT2A (0.65) | HTTPOLBKMT2AMEN1MAPT | |
| SCHEMBL11768631 | 0.85 | MEN1 (0.60) | HTTPOLBKMT2AMEN1MAPT | |
| SCHEMBL11770038 | 0.84 | KMT2A (0.68) | HTTPOLBKMT2AMEN1MAPT | |
| SCHEMBL11768427 | 0.81 | MEN1 (0.67) | HTTPOLBKMT2AMEN1MAPT | |
| SCHEMBL6939392 | 0.79 | MEN1 (0.79) | HTTPOLBKMT2AMEN1MAPT | |
| SCHEMBL11768264 | 0.77 | MEN1 (0.69) | HTTPOLBKMT2AMEN1MAPT | |
| SCHEMBL27929224 | 0.77 | HTT (0.66) | HTTPOLBKMT2AMEN1MAPT | |
| SCHEMBL11768574 | 0.77 | MEN1 (0.58) | HTTPOLBKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3970752-A | Coccidiocidal compositions utilizing 1-phenyl-substituted 1,3,5-triazine | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-20 | — | — | US | disclosed |
| US-3948893-A | COCCIDIOSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | disclosed |