Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.59 |
| ▸ | RAD52 | P43351 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 3/20 | 0.48 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11768617 | 0.99 | POLB (0.58) | POLBRAD52KDM4EALDH1A1GAA | |
| SCHEMBL11770423 | 0.88 | RAD52 (0.63) | POLBRAD52ALDH1A1RAB9ATERT | |
| SCHEMBL29628876 | 0.88 | RAD52 (0.63) | POLBRAD52ALDH1A1RAB9ATERT | |
| SCHEMBL11770198 | 0.88 | SLC2A1 (0.43) | POLBRAD52KDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL10942278 | 0.87 | RAD52 (0.62) | POLBRAD52ALDH1A1RAB9ATERT | |
| Hydrochloric Acid SCHEMBL11772379 | 0.87 | SLC2A1 (0.45) | POLBRAD52KDM4EGAARAB9A | |
| Hydrochloric Acid SCHEMBL11774095 | 0.87 | SLC2A1 (0.45) | SLC2A1 | |
| Hydrochloric Acid SCHEMBL11767117 | 0.87 | SLC2A1 (0.45) | POLBRAD52KDM4EGAARAB9A | |
| Hydrochloric Acid SCHEMBL11766221 | 0.84 | SLC2A1 (0.42) | POLBRAD52KDM4EGAARAB9A | |
| Hydrochloric Acid SCHEMBL11769959 | 0.84 | RAD52 (0.57) | POLBRAD52ALDH1A1RAB9ATERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013665-A | ANTIVIRAL, SUBSTITUTED 1,3-DIMETHYL-1H-PYRAZOLO(3,4B)QUINOLINES | BRISTOL-MYERS COMPANY (US) | 1977-03-22 | — | — | US | disclosed |