Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11742528 | 0.89 | CNR2 (0.44) | CNR2CNR1KDRMEN1GAA | |
| SCHEMBL11772167 | 0.87 | CNR2 (0.40) | CNR2CNR1KDR | |
| SCHEMBL11775561 | 0.86 | CNR2 (0.37) | CNR2CNR1KDRPTPN1TRPA1 | |
| SCHEMBL11743076 | 0.85 | CNR2 (0.38) | CNR2CNR1KDRPTPN1TRPA1 | |
| SCHEMBL11777798 | 0.84 | CNR2 (0.39) | CNR2CNR1KDRPTPN1TRPA1 | |
| SCHEMBL31544855 | 0.82 | CNR2 (0.54) | CNR2CNR1KDRMEN1GAA | |
| SCHEMBL11758555 | 0.82 | CNR2 (0.54) | CNR2CNR1KDRMEN1GAA | |
| SCHEMBL11771583 | 0.82 | CNR2 (0.37) | CNR2CNR1KDRPTPN1TRPA1 | |
| SCHEMBL11794288 | 0.81 | CNR2 (0.41) | CNR2CNR1KDRMEN1GAA | |
| SCHEMBL11742241 | 0.80 | CNR2 (0.46) | CNR2CNR1KDRMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051152-A | TRANQUILIZERS, ANALGESICS | SHARPS ASSOCIATES (US) | 1977-09-27 | — | — | US | disclosed |