SCHEMBL11773916

SCHEMBL11773916

c1ccc(C2CO2)c(C2CCCC2)c1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.38
PTGS2 P35354 1/20 0.37
CEL P19835 2/20 0.36
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
TDO2 P48775 2/20 0.34
HTR2C P28335 2/20 0.34
HTR1D P28221 2/20 0.34
HTR1B P28222 2/20 0.34
PARP1 P09874 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
HTR1A P08908 1/20 0.33
HTR7 P34969 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11770973 0.98 TSHR (0.41) TSHRPTGDR2PTGS2CELCHRNB4
SCHEMBL779938 0.83 CHRNB4 (0.46) PTGDR2PTGS2CELCHRNB4CHRNA3
SCHEMBL13116602 0.83 TSHR (0.40) TSHRCHRNB4CHRNA3
SCHEMBL37732 0.83 TSHR (0.57) TSHRCHRNB4CHRNA3PARP1
SCHEMBL42781 0.81 PTGDR2 (0.48) PTGDR2PTGS2CELCHRNB4CHRNA3
Benzene SCHEMBL27853973 0.79 PTGDR2 (0.52) PTGDR2PTGS2CELCHRNB4CHRNA3
SCHEMBL13116587 0.78 TSHR (0.43) TSHRCHRNB4CHRNA3HTR2C
SCHEMBL13116606 0.77 TSHR (0.41) TSHRCHRNB4CHRNA3
Hydrogen Peroxide SCHEMBL11398422 0.77 PTGDR2 (0.55) PTGDR2PTGS2CELCHRNB4CHRNA3
Hydrogen Peroxide SCHEMBL3679819 0.77 PTGDR2 (0.55) PTGDR2PTGS2CELCHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514800-A Preparation method of penehyclidine hydrochloride 湖南一格制药有限公司 2023-08-01 CN claimed
CN-111925281-B Preparation method of penehyclidine hydrochloride impurity 2-cyclopentyl-2-phenylacetaldehyde 江苏恩华药业股份有限公司 2022-04-15 CN claimed
CN-111925281-A Preparation method of penehyclidine hydrochloride impurity 2-cyclopentyl-2-phenylacetaldehyde 江苏恩华药业股份有限公司 2020-11-13 CN claimed
CN-118480037-A Preparation method of penehyclidine hydrochloride 重庆先洋医药科技有限公司 2024-08-13 CN disclosed
CN-116514800-A Preparation method of penehyclidine hydrochloride 湖南一格制药有限公司 2023-08-01 CN disclosed
CN-116514800-A Preparation method of penehyclidine hydrochloride 湖南一格制药有限公司 2023-08-01 CN disclosed
CN-111925281-B Preparation method of penehyclidine hydrochloride impurity 2-cyclopentyl-2-phenylacetaldehyde 江苏恩华药业股份有限公司 2022-04-15 CN disclosed
CN-111925281-A Preparation method of penehyclidine hydrochloride impurity 2-cyclopentyl-2-phenylacetaldehyde 江苏恩华药业股份有限公司 2020-11-13 CN disclosed
US-3939213-A Preparation of polyalkoxyalkyl compounds UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-02-17 US disclosed