Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10314843 | 0.79 | IDO1 (0.55) | IDO1TAAR1AOC3SLC6A2SLC6A4 | |
| SCHEMBL18596801 | 0.76 | IDO1 (0.52) | IDO1TAAR1AOC3SLC6A2SLC6A4 | |
| SCHEMBL18722577 | 0.74 | IDO1 (0.50) | IDO1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19099546 | 0.73 | IDO1 (0.48) | IDO1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL133145 | 0.72 | TSHR (0.46) | IDO1TAAR1AOC3SLC6A2SLC6A4 | |
| SCHEMBL10775814 | 0.71 | IDO1 (0.47) | IDO1TAAR1PYCR1SLC6A2SLC6A4 | |
| SCHEMBL21466573 | 0.71 | IDO1 (0.47) | IDO1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30377 | 0.71 | IDO1 (0.61) | IDO1TAAR1AOC3SLC6A2SLC6A4 | |
| SCHEMBL8762708 | 0.71 | IDO1 (0.67) | IDO1TAAR1PNMTMAOBMAOA | |
| SCHEMBL3774965 | 0.71 | IDO1 (0.67) | IDO1TAAR1PNMTMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041067-A | AS CATALYST A PALLADIUM, PLATINUM, RHODIUM, CADMIUM, COBALT, ZINC OR COPPER SALT WITH AN AMINE AND AN ALCOHOL | ATLANTIC RICHFIELD COMPANY (US) | 1977-08-09 | — | — | US | disclosed |