Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ABL2 | P42684 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11702251 | 0.94 | APEX1 (0.57) | APEX1POLBCTDSP1L3MBTL1EGFR | |
| SCHEMBL1636289 | 0.88 | POLB (0.55) | APEX1POLBCTDSP1L3MBTL1EGFR | |
| Water SCHEMBL7466907 | 0.86 | POLB (0.54) | APEX1POLBCTDSP1L3MBTL1EGFR | |
| SCHEMBL11776014 | 0.85 | TDP1 (0.57) | APEX1POLBCTDSP1L3MBTL1EGFR | |
| SCHEMBL11582680 | 0.82 | TDP1 (0.57) | APEX1POLBCTDSP1L3MBTL1EGFR | |
| SCHEMBL11775516 | 0.82 | TDP1 (0.49) | EGFRABL1ABL2ACLYLMNA | |
| SCHEMBL11777951 | 0.80 | TDP1 (0.53) | APEX1POLBCTDSP1L3MBTL1LMNA | |
| SCHEMBL11775484 | 0.79 | SMN1; SMN2 (0.57) | APEX1POLBCTDSP1L3MBTL1LMNA | |
| SCHEMBL11780056 | 0.79 | MEN1 (0.56) | APEX1POLBCTDSP1L3MBTL1LMNA | |
| SCHEMBL11775259 | 0.79 | POLB (0.47) | APEX1POLBCTDSP1L3MBTL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3932419-A | QUINOLINE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |