SCHEMBL11780321

SCHEMBL11780321

C[CH]CCc1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.54
HSPA5 P11021 1/20 0.50
MPO P05164 5/20 0.48
SLC6A4 P31645 2/20 0.48
HTR1A P08908 1/20 0.48
IDO1 P14902 2/20 0.47
CYP2D6 P10635 1/20 0.45
TSHR P16473 1/20 0.45
HIF1A Q16665 1/20 0.45
HRH3 Q9Y5N1 3/20 0.44
AKR1B1 P15121 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29056126 0.83 TAAR1 (0.55) TAAR1HSPA5MPOSLC6A4HTR1A
SCHEMBL29056125 0.83 TAAR1 (0.55) TAAR1HSPA5MPOSLC6A4HTR1A
SCHEMBL3080064 0.79 TAAR1 (0.50) TAAR1HSPA5MPOSLC6A4HTR1A
Ethane SCHEMBL10694585 0.79 TAAR1 (0.65) TAAR1HSPA5MPOSLC6A4HTR1A
SCHEMBL911043 0.78 TAAR1 (0.54) TAAR1HSPA5MPOSLC6A4HTR1A
SCHEMBL5543573 0.78 TAAR1 (0.54) TAAR1HSPA5MPOSLC6A4HTR1A
SCHEMBL1222973 0.78 TAAR1 (0.71) TAAR1HSPA5MPOSLC6A4HTR1A
SCHEMBL29706272 0.78 TAAR1 (0.71) TAAR1HSPA5MPOSLC6A4HTR1A
SCHEMBL10582997 0.78 TAAR1 (0.53) TAAR1HSPA5MPOSLC6A4HTR1A
SCHEMBL4203494 0.77 HSPA5 (0.54) TAAR1HSPA5MPOSLC6A4HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3993437-A Process for the dyeing of polyamide fibers with sulphur dyestuffs CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-11-23 US disclosed