Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PTPRC | P08575 | 3/20 | 0.42 |
| ▸ | S100A4 | P26447 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11780494 | 1.00 | HSP90AA1 (0.57) | HSP90AA1MAPTMEN1KMT2APTPRC | |
| SCHEMBL11781232 | 0.89 | HSP90AA1 (0.64) | HSP90AA1MAPTMEN1KMT2APTPRC | |
| SCHEMBL11781236 | 0.89 | HSP90AA1 (0.64) | HSP90AA1MAPTMEN1KMT2APTPRC | |
| SCHEMBL11783416 | 0.88 | HSP90AA1 (0.57) | HSP90AA1MAPTMEN1KMT2APTPRC | |
| SCHEMBL11783419 | 0.88 | HSP90AA1 (0.57) | HSP90AA1MAPTMEN1KMT2APTPRC | |
| SCHEMBL11781071 | 0.88 | HSP90AA1 (0.66) | HSP90AA1MAPTMEN1KMT2APTPRC | |
| SCHEMBL11781076 | 0.88 | HSP90AA1 (0.66) | HSP90AA1MAPTMEN1KMT2APTPRC | |
| SCHEMBL11782222 | 0.85 | MAPT (0.61) | HSP90AA1MAPTMEN1KMT2APTPRC | |
| SCHEMBL11782230 | 0.85 | MAPT (0.61) | HSP90AA1MAPTMEN1KMT2APTPRC | |
| SCHEMBL11781099 | 0.85 | MAPT (0.57) | HSP90AA1MAPTMEN1KMT2APTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935009-A | FLUOREN-9-YLIDENE | OCE-VAN DER GRINTEN N.V. (NL) | 1976-01-27 | — | — | US | disclosed |