SCHEMBL11780809

SCHEMBL11780809

Nc1cccc(-c2ncnc(-c3cccc(N)c3)n2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.56
KDM4E B2RXH2 2/20 0.56
ALDH1A1 P00352 2/20 0.56
LMNA P02545 2/20 0.56
MAPT P10636 2/20 0.56
HPGD P15428 2/20 0.56
KMT2A Q03164 2/20 0.56
MAP4K4 O95819 6/20 0.52
GLA P06280 1/20 0.51
ENPP2 Q13822 1/20 0.50
MAOA P21397 1/20 0.50
ATAD2 Q6PL18 1/20 0.50
NPC1 O15118 2/20 0.47
RAB9A P51151 1/20 0.47
METAP2 P50579 1/20 0.46
PSIP1 O75475 1/20 0.46
AXL P30530 1/20 0.46
MKNK1 Q9BUB5 1/20 0.46
MKNK2 Q9HBH9 1/20 0.46
PIK3CD O00329 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16614073 0.91 MEN1 (0.61) MEN1KDM4EALDH1A1LMNAMAPT
SCHEMBL31158154 0.87 KDM4E (0.49) MEN1KDM4EALDH1A1LMNAMAPT
SCHEMBL31158156 0.83 MAP4K4 (0.52) MEN1KDM4EALDH1A1LMNAMAPT
SCHEMBL15690756 0.81 MEN1 (0.75) MEN1KDM4EALDH1A1LMNAMAPT
SCHEMBL11584762 0.81 MEN1 (0.75) MEN1KDM4EALDH1A1LMNAMAPT
SCHEMBL2885661 0.79 MEN1 (0.51) MEN1KDM4EALDH1A1LMNAMAPT
SCHEMBL2627252 0.78 MAP4K4 (0.60) MEN1KDM4EALDH1A1LMNAMAPT
SCHEMBL13860823 0.78 MEN1 (0.59) MEN1KDM4EALDH1A1LMNAMAPT
SCHEMBL31097206 0.78 MAP4K4 (0.35) MEN1KDM4EALDH1A1LMNAMAPT
SCHEMBL16614069 0.78 MEN1 (0.74) MEN1KDM4EALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3944547-A Iminoisoindolinone pigments CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed