Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.65 |
| ▸ | STS | P08842 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | SHBG | P04278 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | PGR | P06401 | 3/20 | 0.65 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.65 |
| ▸ | AR | P10275 | 3/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.65 |
| ▸ | SNCA | P37840 | 3/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.65 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.65 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.65 |
| ▸ | HTR2B | P41595 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11783204 | 1.00 | ESR1 (0.65) | ESR1ESR2STSHSD17B10SHBG | |
| SCHEMBL11786612 | 0.94 | STS (0.62) | ESR1ESR2STSHSD17B10SHBG | |
| SCHEMBL11786605 | 0.94 | STS (0.62) | ESR1ESR2STSHSD17B10SHBG | |
| SCHEMBL11785373 | 0.93 | STS (0.61) | ESR1ESR2STSHSD17B10SHBG | |
| SCHEMBL11785382 | 0.93 | STS (0.61) | ESR1ESR2STSHSD17B10SHBG | |
| SCHEMBL11785210 | 0.91 | ESR1 (0.67) | ESR1ESR2STSHSD17B10SHBG | |
| SCHEMBL11785215 | 0.91 | ESR1 (0.67) | ESR1ESR2STSHSD17B10SHBG | |
| SCHEMBL7820061 | 0.86 | ESR1 (0.70) | ESR1ESR2STSHSD17B10SHBG | |
| SCHEMBL7831343 | 0.86 | ESR1 (0.70) | ESR1ESR2STSHSD17B10SHBG | |
| SCHEMBL11786700 | 0.86 | ESR1 (0.73) | ESR1ESR2STSHSD17B10SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3946052-A | 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs thereof having postcoital antifertility activity | STANFORD RESEARCH INSTITUTE (US) | 1976-03-23 | — | — | US | disclosed |