Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782292 | 0.81 | MGAM (0.46) | CBFBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL16342366 | 0.81 | CBFB (0.45) | CBFBMAPTL3MBTL1ADAMTS5EGLN1 | |
| SCHEMBL12724890 | 0.79 | CBFB (0.44) | CBFBMAPTADAMTS5EGLN1OPRM1 | |
| SCHEMBL6985345 | 0.74 | CBFB (0.40) | CBFBMAPTADAMTS5EGLN1OPRM1 | |
| SCHEMBL353026 | 0.74 | CBFB (0.51) | CBFBMAPTADAMTS5EGLN1OPRM1 | |
| Hydrochloric Acid SCHEMBL11784418 | 0.73 | EGLN1 (0.40) | CBFBMAPTADAMTS5EGLN1OPRM1 | |
| SCHEMBL4386791 | 0.71 | CBFB (0.49) | CBFBMAPTADAMTS5EGLN1OPRM1 | |
| SCHEMBL1192237 | 0.71 | NPC1 (0.50) | CBFBMAPTADAMTS5EGLN1OPRM1 | |
| SCHEMBL9144161 | 0.71 | CBFB (0.49) | CBFBMAPTADAMTS5EGLN1OPRM1 | |
| SCHEMBL2541920 | 0.71 | CBFB (0.49) | CBFBMAPTMEN1KMT2AADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935314-A | Anti-hypertensive compositions of benzimidazole derivatives | BEECHAM GROUP LIMITED (EN) | 1976-01-27 | — | — | US | claimed |
| US-3935314-A | Anti-hypertensive compositions of benzimidazole derivatives | BEECHAM GROUP LIMITED (EN) | 1976-01-27 | — | — | US | disclosed |