Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.36 |
| ▸ | KDM4A | O75164 | 6/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795156 | 0.87 | FFAR4 (0.46) | FFAR4FFAR1ACACBACACAKDM4C | |
| SCHEMBL11787985 | 0.85 | FFAR4 (0.48) | FFAR4FFAR1ACACBACACAKDM4C | |
| SCHEMBL11783701 | 0.84 | FFAR4 (0.71) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11783707 | 0.84 | FFAR4 (0.71) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11783712 | 0.84 | FFAR4 (0.71) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11784174 | 0.84 | FFAR4 (0.71) | FFAR4FFAR1TBXA2RPTGFRPTGER2 | |
| SCHEMBL11786835 | 0.84 | KDM4C (0.50) | FFAR4FFAR1KDM4CKDM4APHF8 | |
| SCHEMBL11601969 | 0.82 | FFAR4 (0.46) | FFAR4FFAR1ACACBACACAKDM4C | |
| SCHEMBL11792462 | 0.81 | FFAR4 (0.45) | FFAR4FFAR1ACACBACACAKDM4C | |
| SCHEMBL11786566 | 0.81 | MAPT (0.50) | FFAR4FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987091-A | RENAL VASODILATORS | MERCK & CO., INC. (US) | 1976-10-19 | — | — | US | disclosed |