SCHEMBL11786151

SCHEMBL11786151

CC(Oc1ccc(NCc2ccc(O)cc2)cc1)C(Cl)(Cl)Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.53
MAPT P10636 5/20 0.53
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
BLM P54132 3/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
ALDH1A1 P00352 3/20 0.53
POLB P06746 2/20 0.53
HPGD P15428 2/20 0.53
ALOX15 P16050 2/20 0.53
MAPK1 P28482 2/20 0.53
CASP1 P29466 2/20 0.53
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 1/20 0.53
HSP90AA1 P07900 1/20 0.53
HSP90AB1 P08238 1/20 0.53
THRB P10828 1/20 0.53
PLEC Q15149 1/20 0.53
APAF1 O14727 1/20 0.53
USP2 O75604 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28829409 0.85 MEN1 (0.62) GAAMAPTMEN1KMT2ABLM
SCHEMBL11782909 0.85 MAPT (0.52) GAAMAPTMEN1KMT2ABLM
SCHEMBL28846873 0.79 MAPT (0.70) GAAMAPTMEN1KMT2ABLM
SCHEMBL5863587 0.79 MAPT (0.70) GAAMAPTMEN1KMT2ABLM
SCHEMBL24690514 0.75 MAPT (0.64) GAAMAPTMEN1KMT2ABLM
SCHEMBL10055010 0.74 MAPT (0.80) GAAMAPTMEN1KMT2ABLM
SCHEMBL6795311 0.74 MAPT (0.80) GAAMAPTMEN1KMT2ABLM
SCHEMBL6555845 0.72 GAA (0.66) GAAMAPTMEN1KMT2ABLM
SCHEMBL11449057 0.70 MEN1 (0.50) GAAMAPTMEN1KMT2AL3MBTL1
SCHEMBL6555950 0.70 MAPT (1.00) GAAMAPTMEN1KMT2ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3941842-A INSECTICIDE, LARVICIDE THE UNIVERSITY OF ILLINOIS FOUNDATION (US) 1976-03-02 US disclosed