SCHEMBL11786757

SCHEMBL11786757

CC1(C)CC(O)CC(C)(C)N1CCCCCCCCO

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.31
GBA1 P04062 1/20 0.30
CYP2D6 P10635 1/20 0.30
LMNA P02545 2/20 0.30
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30
MEN1 O00255 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11789376 1.00 KMT2A (0.31) KMT2AGBA1CYP2D6LMNAALDH1A1
SCHEMBL11787175 1.00 KMT2A (0.31) KMT2AGBA1CYP2D6LMNAALDH1A1
SCHEMBL11632563 0.92 KMT2A (0.33) KMT2ACYP2D6
SCHEMBL9972712 0.90 KMT2A (0.34) KMT2ACYP2D6
SCHEMBL9972715 0.86 KMT2A (0.34) KMT2ACYP2D6
SCHEMBL11252165 0.85 GUSB (0.43) GBA1
SCHEMBL11273758 0.85 GUSB (0.43) GBA1
SCHEMBL8476235 0.85 GUSB (0.43) GBA1
SCHEMBL8481829 0.85 GUSB (0.43) GBA1
SCHEMBL39066 0.84 KMT2A (0.33) KMT2ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3974127-A Alkylene oxide condensates of tetramethylpiperidine alcohols or glycols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-10 US disclosed