Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785458 | 0.91 | KMT2A (0.97) | KMT2ASMN1; SMN2L3MBTL1MIFASIC3 | |
| Hydrochloric Acid SCHEMBL11781352 | 0.89 | KMT2A (1.00) | KMT2ASMN1; SMN2L3MBTL1MIFASIC3 | |
| SCHEMBL11784098 | 0.88 | KMT2A (0.76) | KMT2ASMN1; SMN2L3MBTL1MIFASIC3 | |
| Hydrochloric Acid SCHEMBL11785563 | 0.87 | KMT2A (0.78) | KMT2ASMN1; SMN2L3MBTL1MIFASIC3 | |
| Hydrochloric Acid SCHEMBL11783670 | 0.80 | KMT2A (0.76) | KMT2ASMN1; SMN2L3MBTL1MIFASIC3 | |
| Hydrochloric Acid SCHEMBL11781344 | 0.78 | KMT2A (0.56) | KMT2AJAK2JAK3KMOCYP1A2 | |
| Hydrochloric Acid SCHEMBL11785641 | 0.77 | KMT2A (0.68) | KMT2ASMN1; SMN2L3MBTL1MIFASIC3 | |
| SCHEMBL11785604 | 0.75 | KMT2A (0.68) | KMT2ASMN1; SMN2L3MBTL1JAK2JAK3 | |
| Hydrochloric Acid SCHEMBL11783714 | 0.74 | KMT2A (0.52) | KMT2AJAK2JAK3KMOCYP1A2 | |
| Bromide SCHEMBL11785196 | 0.74 | KMT2A (0.68) | KMT2ASMN1; SMN2L3MBTL1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950525-A | BRONCHODILATION, 4-HYDROXY-6-ARYL PYRIMIDINES | PFIZER INC. (US) | 1976-04-13 | — | — | US | disclosed |