Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 10/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CA2 | P00918 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.68 |
| ▸ | CA6 | P23280 | 1/20 | 0.68 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.68 |
| ▸ | CA5A | P35218 | 1/20 | 0.68 |
| ▸ | CA7 | P43166 | 1/20 | 0.68 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.68 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.68 |
| ▸ | APP | P05067 | 9/20 | 0.60 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.54 |
| ▸ | AQP1 | P29972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11789083 | 0.91 | CISD1 (0.56) | CISD1CA12ALDH1A1CA1CA2 | |
| SCHEMBL11790865 | 0.91 | CISD1 (0.74) | CISD1CA12ALDH1A1CA1CA2 | |
| SCHEMBL14514065 | 0.85 | CISD1 (0.73) | CISD1CA12ALDH1A1CA1CA2 | |
| SCHEMBL12418660 | 0.84 | CISD1 (0.81) | CISD1CA12ALDH1A1CA1CA2 | |
| SCHEMBL30331814 | 0.84 | CISD1 (0.81) | CISD1CA12ALDH1A1CA1CA2 | |
| SCHEMBL13107613 | 0.83 | CISD1 (0.76) | CISD1CA12ALDH1A1CA1CA2 | |
| Furosemide SCHEMBL27607809 | 0.83 | CISD1 (0.81) | CISD1CA12ALDH1A1CA1CA2 | |
| SCHEMBL11789073 | 0.82 | CISD1 (0.45) | CISD1CA12ALDH1A1CA1CA2 | |
| SCHEMBL11787100 | 0.82 | CISD1 (0.68) | CISD1CA12ALDH1A1CA1CA2 | |
| Furosemide SCHEMBL27537915 | 0.82 | CISD1 (0.92) | CISD1CA12ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991188-A | SALURETICS | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-11-09 | — | — | US | disclosed |