Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL653934 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1TDP1CHRNA7CHRNB4 | |
| Bromide SCHEMBL28903217 | 0.98 | KDM4E (0.56) | KDM4EALDH1A1TDP1CHRNA7CHRNB4 | |
| Ammonia Solution, Strong SCHEMBL27849718 | 0.98 | CHRNA7 (0.50) | KDM4EALDH1A1TDP1CHRNA7CHRNB4 | |
| Bromide SCHEMBL653935 | 0.98 | CHRNA7 (0.50) | KDM4EALDH1A1TDP1CHRNA7CHRNB4 | |
| Hydrochloric Acid SCHEMBL3641370 | 0.98 | CHRNA7 (0.50) | KDM4EALDH1A1TDP1CHRNA7CHRNB4 | |
| Bromide SCHEMBL3646711 | 0.98 | CHRNA7 (0.50) | KDM4EALDH1A1TDP1CHRNA7CHRNB4 | |
| Bromide SCHEMBL3641371 | 0.98 | KDM4E (0.56) | KDM4EALDH1A1TDP1CHRNA7CHRNB4 | |
| Water SCHEMBL3646710 | 0.98 | CHRNA7 (0.50) | KDM4EALDH1A1TDP1CHRNA7CHRNB4 | |
| SCHEMBL81238 | 0.97 | KDM4E (0.54) | KDM4EALDH1A1TDP1CHRNA7CHRNB4 | |
| Hydrogen Sulfide SCHEMBL5998579 | 0.97 | KDM4E (0.54) | KDM4EALDH1A1TDP1CHRNA7CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6497 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119432438-B | Method for producing lubricating oil base oil from heavy raw materials and lubricating oil base oil obtained by method | PETROCHINA COMPANY LIMITED (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-119708454-B | Bio-based polylactic acid compatilizer, preparation method thereof and full bio-based polylactic acid composite material | NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-117285423-B | Multifunctional acrylic ester and application thereof | 湖南松井先进表面处理与功能涂层研究院有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122036796-A | Method for high-selectivity synthesis of pyridoxine phosphate based on phase transfer catalytic system | 台州职业技术学院 | 2026-05-15 | — | — | CN | claimed |
| CN-122010689-A | Preparation method of cycloparaffin | 浙江清华长三角研究院 | 2026-05-12 | — | — | CN | claimed |
| CN-119431736-B | Aliphatic amine-containing cardanol basic sign mechanical reinforced flame-retardant epoxy resin and preparation method thereof | 中国民用航空飞行学院 | 2026-05-12 | — | — | CN | claimed |
| EP-4522585-B1 | PROCESS FOR THE PREPARATION OF BETA-HYDROXYKETONES | ADAMA AGAN LTD (IL) | 2026-04-08 | — | — | EP | claimed |
| EP-4713317-A1 | A PROCESS FOR PURIFICATION OF ETHOFUMESATE | Adama Agan Ltd. (IL) | 2026-03-25 | — | — | EP | claimed |
| CN-121574042-A | Preparation method of chloromethyl styrene | 江苏扬农化工集团有限公司 | 2026-02-27 | — | — | CN | claimed |
| US-20260014284-A1 | PROCESS FOR PREPARATION OF RADIOLABELED STYRYLPYRIDINES AND PHARMACEUTICAL COMPOSITIONS THEREOF | JUBILANT DRAXIMAGE INC (CA) | 2026-01-15 | — | — | US | claimed |
| EP-0056145-A1 | Process for the production of inorganic-organic foams | Mobay Chemical Corporation (US) | 1982-07-21 | — | — | EP | claimed |
| EP-0004570-B1 | THIOL ESTERS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND A PROCESS FOR PREPARING CEPHALOSPORIN COMPOUNDS USING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-04-14 | — | — | EP | claimed |
| US-4314945-A | CARBONATION IN THE PRESENCE OF A QUATERNARY AMMONIUM OR POTAS0IUM SALT CATALYST | UNION CARBIDE CORPORATION (US) | 1982-02-09 | — | — | US | claimed |
| US-4293702-A | FROM 2-ALKOXYBENZOTHIAZOLES; CATALYST OF TERTIARY AMINE, QUATERNARY AMMONIUM COMPOUND OR DIALKYL SULFATE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-10-06 | — | — | US | claimed |
| US-4226624-A | CORROSION RESISTANCE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1980-10-07 | — | — | US | claimed |
| EP-0004570-A1 | Thiol esters, process for their preparation, pharmaceutical compositions containing them and a process for preparing cephalosporin compounds using the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1979-10-17 | — | — | EP | claimed |
| US-4144264-A | Process for producing a 3-methyl-2-(4-halophenyl)butyronitrile | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-03-13 | — | — | US | claimed |
| US-4140516-A | Encapsulation process employing phase transfer catalysts | STAUFFER CHEMICAL COMPANY (US) | 1979-02-20 | — | — | US | claimed |
| US-4125521-A | FROM AN EPOXYALKANE, POLYHYDRIC ALCOHOL AND CYCLIC DICARBOXYLIC ACID | DAICEL LTD. (JP) | 1978-11-14 | — | — | US | claimed |
| US-4012428-A | Method for preparing 3-methyl-2-(4-halogenophenyl)-butyronitrile | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-03-15 | — | — | US | claimed |