Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1142572 | 0.98 | TSHR (0.39) | TSHROPRM1TRPA1DDAH1GAPDH | |
| SCHEMBL1142296 | 0.98 | TSHR (0.39) | TSHROPRM1TRPA1DDAH1GAPDH | |
| SCHEMBL1142254 | 0.98 | TSHR (0.39) | TSHROPRM1TRPA1DDAH1GAPDH | |
| SCHEMBL1142376 | 0.98 | TSHR (0.39) | TSHROPRM1TRPA1DDAH1GAPDH | |
| SCHEMBL11184033 | 0.93 | — | — | |
| SCHEMBL19356850 | 0.86 | TSHR (0.39) | TSHROPRM1TRPA1DDAH1GAPDH | |
| SCHEMBL892183 | 0.84 | TSHR (0.37) | TSHROPRM1TRPA1DDAH1GAPDH | |
| SCHEMBL8056247 | 0.83 | — | — | |
| SCHEMBL11872478 | 0.83 | ABCB1 (0.35) | TSHROPRM1ZDHHC7ALDH1A1ABCB1 | |
| SCHEMBL1715275 | 0.82 | TSHR (0.41) | TSHROPRM1LMNAADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462297-B2 | Chiral dopants having a laterally alkylated phenyl structural element | MERCK PATENT GMBH (DE) | 2008-12-09 | — | — | US | disclosed |
| US-3974092-A | COMPOUND, 6B, ORGANOALUMINUM COMPOUND, ETHER OF OLEFIN ALCOHOL | CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |