Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PTGFR | P43088 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11791284 | 0.91 | FFAR4 (0.69) | FFAR4FFAR1GPR84FAAHMEN1 | |
| SCHEMBL11791279 | 0.91 | FFAR4 (0.69) | FFAR4FFAR1GPR84FAAHMEN1 | |
| SCHEMBL11791276 | 0.91 | FFAR4 (0.69) | FFAR4FFAR1GPR84FAAHMEN1 | |
| SCHEMBL11796421 | 0.85 | ACE2 (0.51) | FFAR4FFAR1GPR84FAAHNFKB1 | |
| SCHEMBL11790008 | 0.85 | PRSS1 (0.53) | FFAR4FFAR1MEN1KMT2AKDM4E | |
| SCHEMBL227566 | 0.85 | FFAR4 (0.71) | FFAR4FFAR1GPR84FAAHNFKB1 | |
| SCHEMBL19475125 | 0.85 | FFAR4 (0.71) | FFAR4FFAR1GPR84FAAHNFKB1 | |
| Octadecanoic Acid Amide SCHEMBL5617445 | 0.85 | FFAR4 (0.71) | FFAR4FFAR1GPR84FAAHNFKB1 | |
| SCHEMBL19066822 | 0.85 | FFAR4 (0.71) | FFAR4FFAR1GPR84FAAHNFKB1 | |
| SCHEMBL21585875 | 0.85 | FFAR4 (0.71) | FFAR4FFAR1GPR84FAAHNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989749-A | RENAL VASODILATORS, ANTITHROMBUS | MERCK & CO., INC. (US) | 1976-11-02 | — | — | US | disclosed |