Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11760134 | 0.78 | CA1 (0.45) | CA1CA2ZDHHC7SMN1; SMN2METAP1 | |
| SCHEMBL19105417 | 0.78 | SMN1; SMN2 (0.48) | CA1CA2ZDHHC7SMN1; SMN2METAP1 | |
| SCHEMBL7099340 | 0.76 | CA1 (0.40) | CA1CA2ZDHHC7SMN1; SMN2ABCB1 | |
| SCHEMBL27406044 | 0.76 | CHRM1 (0.48) | CA2METAP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL24555610 | 0.75 | ZDHHC7 (0.48) | CA1CA2ZDHHC7SMN1; SMN2METAP1 | |
| SCHEMBL21816847 | 0.75 | METAP1 (0.44) | CA1CA2ZDHHC7SMN1; SMN2METAP1 | |
| Hydrochloric Acid SCHEMBL28698262 | 0.73 | METAP1 (0.42) | CA1CA2ZDHHC7SMN1; SMN2METAP1 | |
| SCHEMBL10596596 | 0.73 | CA1 (0.41) | CA1CA2ZDHHC7SMN1; SMN2METAP1 | |
| Hydrochloric Acid SCHEMBL28690536 | 0.73 | METAP1 (0.42) | CA1CA2ZDHHC7SMN1; SMN2METAP1 | |
| SCHEMBL10733934 | 0.73 | SMN1; SMN2 (0.41) | CA1CA2SMN1; SMN2CA14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969381-A | 13,14-Dihydro-16-fluoro prostaglandin B1 analogs | THE UPJOHN COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3969380-A | 16-Fluoro prostaglandin F2 analogs | THE UPJOHN COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3969379-A | 13,14-Dihydro-16-fluoro prostaglandin A1 analogs | THE UPJOHN COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3969377-A | 16-Fluoro prostaglandin E1 analogs | THE UPJOHN COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3969378-A | 16-Fluoro prostaglandin A2 analogs | THE UPJOHN COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3969376-A | 13,14-Dihydro-16-fluoro prostaglandin E1 analogs | THE UPJOHN COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3962293-A | 13,14-Dihydro-16-fluoro prostaglandin F1 | THE UPJOHN COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3931279-A | 5-Oxa prostaglandin F2.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-06 | — | — | US | disclosed |