SCHEMBL1179741

SCHEMBL1179741

Nc1nc(=O)[nH]cc1C=O

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.34
IMPDH2 P12268 1/20 0.34
KMT2A Q03164 1/20 0.34
CCNT1 O60563 1/20 0.33
CDK9 P50750 1/20 0.33
HASPIN Q8TF76 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
TRIM24 O15164 1/20 0.31
TRIM33 Q9UPN9 1/20 0.31
PLG P00747 1/20 0.30
PLAU P00749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17224027 0.91 KMT2A (0.30) CYP2A6IMPDH2KMT2A
SCHEMBL29714131 0.86 KMT2A (0.32) CYP2A6IMPDH2KMT2ACCNT1CDK9
SCHEMBL21223630 0.85 KDM3B (0.33) KDM4E
SCHEMBL16432349 0.85 SUMO1 (0.33) CYP2A6IMPDH2KMT2A
SCHEMBL3823196 0.82 DPYD (0.42)
SCHEMBL532662 0.79 DPYD (0.31)
SCHEMBL8997737 0.79 DPYD (0.31)
SCHEMBL2827577 0.79 KDM5A (0.31)
SCHEMBL11153548 0.79
SCHEMBL932306 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3437 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
EP-4727953-A2 ACCELERATED MARKING OF 5-FORMYL CYTOSINE AND USE IN NUCLEIC ACID METHYLATION SEQUENCING F. Hoffmann-La Roche AG (CH) 2026-04-22 EP claimed
US-12606866-B2 Methods for the amplification of bisulfite-treated DNA THE UNIVERSITY OF CHICAGO (US) 2026-04-21 US claimed
US-20260103701-A1 TET-ASSISTED PYRIDINE BORANE SEQUENCING EXACT SCIENCES INNOVATION LTD (GB) 2026-04-16 US claimed
US-12601006-B2 Targeted, long-read nucleic acid sequencing for the determination of cytosine modifications LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (CH) 2026-04-14 US claimed
US-20260098287-A1 METHOD AND KIT FOR REGENERATING REUSABLE INITIATORS FOR NUCLEIC ACID SYNTHESIS CHENG-YAO CHEN (TW) 2026-04-09 US claimed
EP-4713485-A2 SEQUENCING ADAPTERS FOR METHYLATION SEQUENCING Foundation Medicine, Inc. (US) 2026-03-25 EP claimed
US-20140127678-A1 Mapping Cytosine Modifications BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2014-05-08 US claimed
WO-2014071250-A1 METHODS FOR DETECTING AND MAPPING MODIFICATIONS TO NUCLEIC ACID POLYMERS USING NANOPORE SYSTEMS UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2014-05-08 WO claimed
US-20130244237-A1 Methods and Compositions for Discrimination Between Cytosine and Modifications Thereof and for Methylome Analysis NEW ENGLAND BIOLABS, INC. (US) 2013-09-19 US claimed
WO-2013138644-A2 METHODS AND COMPOSITIONS FOR DISCRIMINATION BETWEEN CYTOSINE AND MODIFICATIONS THEREOF, AND FOR METHYLOME ANALYSIS NEW ENGLAND BIOLABS, INC. (US) 2013-09-19 WO claimed
WO-2013090588-A1 METHODS AND KITS FOR DETECTION OF METHYLATION STATUS OSLO UNIVERSITETSSYKEHUS HF (NO) 2013-06-20 WO claimed
WO-2013057202-A1 EPIGENETIC MARKER FOR THE IDENTIFICATION OF IL17 POSITIVE T CELLS IN COMPLEX SAMPLES EPIONTIS GMBH (DE) 2013-04-25 WO claimed
WO-2013017853-A2 METHODS FOR DETECTION OF NUCLEOTIDE MODIFICATION CAMBRIDGE EPIGENETIX LIMITED (GB) 2013-02-07 WO claimed
US-20070161585-A1 Immunopotentiator and method for enhancing immunoactivity using the same JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2007-07-12 US claimed
EP-1702620-A1 IMMUNOPOTENTIATOR AND METHOD OF ENHANCING IMMUNOLOGICAL ACTIVITY WITH THE SAME Japan Science and Technology Agency (JP) 2006-09-20 EP claimed
WO-1993000099-A2 USE OF PYRIMIDINE AND PURINE NUCLEOSIDES FOR THE PROPHYLAXIS AND/OR TREATMENT OF INFECTIONS CAUSED BY ADENOVIRUSES Max-Delbrück-Centrum für Molekulare Medizin (DE) 1993-01-07 WO claimed