Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | ACACA | Q13085 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131999 | 0.86 | NPC1 (0.53) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL9152375 | 0.84 | CA4 (0.68) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL17283658 | 0.84 | CA4 (0.68) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| Biphenyl SCHEMBL11784329 | 0.84 | CA4 (0.68) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL291776 | 0.84 | CA4 (0.68) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| Water SCHEMBL1023367 | 0.81 | CA4 (0.65) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| Hydrogen Sulfide SCHEMBL27551138 | 0.81 | CA4 (0.65) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| Water SCHEMBL3540832 | 0.81 | CA4 (0.65) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL28478235 | 0.81 | CA4 (0.65) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| Bromide SCHEMBL27478794 | 0.81 | CA4 (0.65) | NPC1RAB9AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3955977-A | GRAPHIC DISPLAYS | XEROX CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3952035-A | Organic compounds | SANDOZ LTD., (SANDOZ AG) (CH) | 1976-04-20 | — | — | US | disclosed |