SCHEMBL11798707

SCHEMBL11798707

COCCCCOc1cc(O)c2c(c1N)C(=O)c1ccccc1C2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.43
KMT2A Q03164 8/20 0.43
MAPT P10636 8/20 0.43
MAPK1 P28482 5/20 0.43
KDM4E B2RXH2 5/20 0.43
TDP1 Q9NUW8 4/20 0.43
ALDH1A1 P00352 4/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
HPGD P15428 2/20 0.43
MAOA P21397 2/20 0.43
CYP1A1 P04798 2/20 0.43
BRCA1 P38398 2/20 0.43
DAPK1 P53355 2/20 0.43
TTR P02766 1/20 0.43
CYP3A4 P08684 1/20 0.43
HSPD1 P10809 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
ACHE P22303 1/20 0.43
MAOB P27338 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2256398 0.94 MEN1 (0.44) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL10085670 0.93 MEN1 (0.49) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL10973315 0.90 MEN1 (0.41) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL29403891 0.90 MEN1 (0.41) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL13674420 0.90 PTPN1 (0.44) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL11794662 0.89 MEN1 (0.45) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL11082283 0.89 MEN1 (0.45) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL15603999 0.89 MEN1 (0.45) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL10936284 0.89 MEN1 (0.45) MEN1KMT2AMAPTMAPK1KDM4E
SCHEMBL2833211 0.87 MEN1 (0.43) MEN1KMT2AMAPTMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3968131-A POLYOXYETHYLENE GLYCOL BASF AKTIENGESELLSCHAFT (DT) 1976-07-06 US disclosed