Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.43 |
| ▸ | CNR1 | P21554 | 7/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11778057 | 0.90 | CNR2 (0.42) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11739108 | 0.87 | — | — | |
| SCHEMBL11744497 | 0.86 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL11874764 | 0.86 | CNR2 (0.37) | CNR2CNR1 | |
| SCHEMBL11796076 | 0.85 | CNR2 (0.37) | CNR2CNR1THRATHRB | |
| Hydrochloric Acid SCHEMBL11741397 | 0.85 | CNR2 (0.37) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL11733906 | 0.84 | CNR2 (0.36) | CNR2CNR1THRATHRB | |
| SCHEMBL11866151 | 0.83 | CNR2 (0.36) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL11737670 | 0.82 | CNR2 (0.35) | CNR2CNR1 | |
| SCHEMBL11678770 | 0.82 | CNR2 (0.44) | CNR2CNR1TRPA1CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3972880-A | TRANQUILIZER | SHARPS ASSOCIATES (US) | 1976-08-03 | — | — | US | disclosed |
| US-3960871-A | ANTIDEPRESSANT, ANALGESICS, ANTICONVULSANT ANTI-ANXIETY ACTIVITY | SHARPS ASSOCIATES (US) | 1976-06-01 | — | — | US | disclosed |