SCHEMBL11799862

SCHEMBL11799862

O=C(O)CCN(CCO)c1ccccc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
GAA P10253 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.42
GMNN O75496 1/20 0.42
LMNA P02545 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
GABRA1 P14867 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
THPO P40225 1/20 0.42
GABRA2 P47869 1/20 0.42
GABRB2 P47870 1/20 0.42
PMP22 Q01453 1/20 0.42
HIF1A Q16665 1/20 0.42
SLCO1B3 Q9NPD5 1/20 0.42
HDAC3 O15379 2/20 0.41
HDAC4 P56524 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2804456 0.92 SMN1; SMN2 (0.47) ALDH1A1SMN1; SMN2GMNNLMNACYP2D6
SCHEMBL10881654 0.87 HPGD (0.49) ALDH1A1GAASMN1; SMN2LMNAL3MBTL1
SCHEMBL78451 0.85 KDM4E (0.46) ALDH1A1GAASMN1; SMN2MAPTTSHR
SCHEMBL11750668 0.84 SMN1; SMN2 (0.47) ALDH1A1GAASMN1; SMN2LMNAMAPT
SCHEMBL13562561 0.84 KMT2A (0.56) ALDH1A1GAASMN1; SMN2LMNAMAPT
Ammonia Solution, Strong SCHEMBL28490308 0.83 KDM4E (0.44) ALDH1A1GAASMN1; SMN2MAPTTSHR
Hydrochloric Acid SCHEMBL28957289 0.83 KDM4E (0.48) ALDH1A1GAASMN1; SMN2LMNAMAPT
Bromide SCHEMBL11628834 0.83 KDM4E (0.44) ALDH1A1GAASMN1; SMN2MAPTTSHR
SCHEMBL11797772 0.83 SMN1; SMN2 (0.41) ALDH1A1SMN1; SMN2GMNNLMNACYP2D6
SCHEMBL9125852 0.83 TP53 (0.51) ALDH1A1LMNATSHRL3MBTL1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3993619-A AZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1976-11-23 US disclosed