Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983959 | 0.87 | TSHR (0.46) | TSHRKDM4EALDH1A1HTTGAA | |
| SCHEMBL3795759 | 0.82 | TSHR (0.44) | TSHRKDM4EALDH1A1HTTGAA | |
| SCHEMBL14301518 | 0.82 | TSHR (0.50) | TSHRKDM4EALDH1A1HTTGAA | |
| SCHEMBL8983971 | 0.78 | TSHR (0.42) | TSHRKDM4EALDH1A1HTTGAA | |
| SCHEMBL16714013 | 0.75 | TSHR (0.32) | TSHRALDH1A1TDP1 | |
| SCHEMBL31168390 | 0.75 | TSHR (0.43) | TSHRKDM4EALDH1A1HTTGAA | |
| SCHEMBL30485899 | 0.75 | TSHR (0.43) | TSHRKDM4EALDH1A1HTTGAA | |
| SCHEMBL6036840 | 0.72 | TSHR (0.45) | TSHRKDM4EALDH1A1HTTGAA | |
| SCHEMBL57480 | 0.69 | TSHR (0.63) | TSHRKDM4EALDH1A1HTTGAA | |
| SCHEMBL2818597 | 0.69 | TSHR (0.63) | TSHRKDM4EALDH1A1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962299-A | Organopolysiloxane polyesters | CELANESE CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |