Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800727 | 1.00 | MAPT (0.58) | MAPTLMNAKMT2AKDM4EL3MBTL1 | |
| SCHEMBL11787988 | 0.85 | MAPT (0.53) | MAPTLMNAKMT2AKDM4EL3MBTL1 | |
| SCHEMBL11787996 | 0.85 | MAPT (0.53) | MAPTLMNAKMT2AKDM4EL3MBTL1 | |
| SCHEMBL11790993 | 0.83 | MAPT (0.65) | MAPTLMNAKMT2AKDM4EL3MBTL1 | |
| SCHEMBL11790981 | 0.83 | MAPT (0.65) | MAPTLMNAKMT2AKDM4EL3MBTL1 | |
| SCHEMBL11793111 | 0.79 | MAPT (0.70) | MAPTLMNAKMT2AKDM4EL3MBTL1 | |
| SCHEMBL11793096 | 0.79 | MAPT (0.70) | MAPTLMNAKMT2AKDM4EL3MBTL1 | |
| SCHEMBL10101737 | 0.78 | NPC1 (0.54) | MAPTLMNAKMT2AKDM4EL3MBTL1 | |
| SCHEMBL11793762 | 0.77 | MAPT (0.56) | MAPTLMNAKMT2AKDM4EL3MBTL1 | |
| SCHEMBL11793757 | 0.77 | MAPT (0.56) | MAPTLMNAKMT2AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3997565-A | METAL COMPLEXING AGENT, DISPERSANT, CARBON BLACK, VIRICIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-12-14 | — | — | US | disclosed |