SCHEMBL1180141

SCHEMBL1180141

OCCOCCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.58
ALDH1A1 P00352 2/20 0.46
RECQL P46063 1/20 0.46
TSHR P16473 3/20 0.46
MAPK1 P28482 1/20 0.46
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
IDO1 P14902 1/20 0.43
LTA4H P09960 1/20 0.43
EPHX2 P34913 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL16085977 1.00 TDP1 (0.58) TDP1ALDH1A1RECQLTSHRMAPK1
SCHEMBL9995347 0.98 TDP1 (0.56) TDP1ALDH1A1RECQLTSHRMAPK1
SCHEMBL4185009 0.98 TDP1 (0.56) TDP1ALDH1A1RECQLTSHRMAPK1
Di(Hydroxyethyl)Ether SCHEMBL11853477 0.93 TDP1 (0.61) TDP1ALDH1A1RECQLTSHRMAPK1
SCHEMBL198134 0.88 TSHR (0.52) TDP1ALDH1A1TSHRCA1CA2
SCHEMBL6041857 0.87 CA9 (0.47) TDP1ALDH1A1CA1CA2CA9
SCHEMBL6268788 0.87 TDP1 (0.54) TDP1TSHRMAPK1CA1CA2
SCHEMBL10390505 0.87 IDO1 (0.55) TDP1ALDH1A1RECQLMAPK1MEN1
Benzyl Alcohol SCHEMBL7506951 0.86 TSHR (0.64) TDP1ALDH1A1TSHRCA1CA2
SCHEMBL6001883 0.85 TDP1 (0.52) TDP1ALDH1A1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119843499-A Electronic fabric with display function and preparation method thereof 复旦大学 2025-04-18 CN claimed
CN-119812361-A Battery preparation process for improving carbon deposition resistance of Ni-based composite ceramic fuel electrode 武汉华夏智能技术有限公司 2025-04-11 CN claimed
CN-119564545-A Simple method for preparing high-dispersity silicon dioxide material, product and application thereof 上海纳米技术及应用国家工程研究中心有限公司 2025-03-07 CN claimed
CN-119507006-A Nickel-free hole sealing method and aluminum alloy product 立铠精密科技(盐城)有限公司 2025-02-25 CN claimed
CN-114846329-B Styrene polymer microsphere with long afterglow luminescence, preparation method and application thereof 复旦大学 2024-07-23 CN claimed
CN-118119591-A Polymerizable raw material comprising recovered bis (2-hydroxyethyl) terephthalate and process for preparing the same SK化学公司 2024-05-31 CN claimed
CN-117946819-A Liquid detergent composition for hard surface 花王株式会社 2024-04-30 CN claimed
CN-117916284-A Polyester resins using recycled bis (2-hydroxyethyl) terephthalate and articles comprising the same SK化学公司 2024-04-19 CN claimed
CN-117845228-A Nitrogen-free ash removal neutralizer, and preparation method and application thereof 日善电脑配件(嘉善)有限公司 2024-04-09 CN claimed
CN-116948198-A Preparation method of high-strength epoxy resin pressure-bearing plugging material and oil-based drilling fluid 西南石油大学 2023-10-27 CN claimed
CN-112924686-A Immunochromatography test strip for detecting serum amyloid A and preparation and detection methods thereof 复旦大学 2021-06-08 CN claimed
EP-3810777-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS Yumanity Therapeutics, Inc. (US) 2021-04-28 EP claimed
US-5604225-A DIETETICS; OBESITY DR. KARL THOMAE GMBH (DE) 1997-02-18 US claimed
US-5457205-A Substituted thiazoles useful for treatment of diabetes DR. KARL THOMAE GMBH (DE) 1995-10-10 US claimed
US-5219852-A Hypoglycemic agents, treatment of diabetes and obesity DR. KARL THOMAE GMBH (DE) 1993-06-15 US claimed
EP-0254856-B1 PYRIDINETHANOL AMINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1991-09-04 EP claimed
EP-0239815-B1 SUBSTITUTED THIAZOLES AND OXAZOLES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION Dr. Karl Thomae GmbH (DE) 1991-07-24 EP claimed
US-5026702-A Enhances physical performance in animals, effective in lowering blood sugar, reducing body fat and lowering atherogenic lipoproteins DR. KARL THOMAE, GMBH (DE) 1991-06-25 US claimed
US-4988714-A Drugs for treatment of obesity and diabetics, increases protein breakdown, for fattening animals HOFFMANN-LA ROCHE INC. (US) 1991-01-29 US claimed
US-4800206-A ANTIDIABETIC AGENTS; HYPOGLYCEMIC AGENTS HOFFMANN-LA ROCHE INC. (US) 1989-01-24 US claimed