Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566581 | 0.86 | TSHR (1.00) | TSHRMAPK1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL10764055 | 0.86 | TSHR (0.76) | TSHRMAPK1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL5069706 | 0.85 | TSHR (0.73) | TSHRMAPK1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL1015707 | 0.85 | TSHR (0.73) | TSHRMAPK1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL6423567 | 0.85 | TSHR (0.73) | TSHRMAPK1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL15988936 | 0.85 | TSHR (0.73) | TSHRMAPK1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL6944861 | 0.85 | MAPK1 (1.00) | TSHRMAPK1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL31474384 | 0.83 | TSHR (0.71) | TSHRMAPK1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL310621 | 0.83 | TSHR (0.71) | TSHRMAPK1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL5076592 | 0.83 | TSHR (0.76) | TSHRMAPK1L3MBTL1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3936462-A | CNS DEPRESSANT, ANALGESIC | STERLING DRUG INC. (US) | 1976-02-03 | — | — | US | disclosed |