Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11801676 | 1.00 | EP300 (0.47) | EP300TSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL31317388 | 0.91 | EP300 (0.50) | EP300TSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL31317422 | 0.88 | EP300 (0.48) | EP300TSHRLMNAHSD17B10ALDH1A1 | |
| SCHEMBL28222807 | 0.88 | EP300 (0.52) | EP300TSHRLMNAHSD17B10KMT2A | |
| SCHEMBL11972786 | 0.88 | EP300 (0.52) | EP300TSHRLMNAHSD17B10KMT2A | |
| SCHEMBL6140916 | 0.88 | EP300 (0.52) | EP300TSHRLMNAHSD17B10KMT2A | |
| SCHEMBL6131754 | 0.88 | EP300 (0.52) | EP300TSHRLMNAHSD17B10KMT2A | |
| SCHEMBL5605179 | 0.88 | EP300 (0.52) | EP300TSHRLMNAHSD17B10KMT2A | |
| SCHEMBL11053878 | 0.85 | EP300 (0.48) | EP300TSHRLMNAHSD17B10KMT2A | |
| SCHEMBL18920446 | 0.84 | EP300 (0.45) | EP300LMNAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3974181-A | Trimethyl-1,4-dioxaspiro[4,5]dec-7-en-8-methanol | HOFFMANN-LA ROCHE INC. (US) | 1976-08-10 | — | — | US | disclosed |
| US-3974181-A | Trimethyl-1,4-dioxaspiro[4,5]dec-7-en-8-methanol | HOFFMANN-LA ROCHE INC. (US) | 1976-08-10 | — | — | US | disclosed |