SCHEMBL11802003

SCHEMBL11802003

O=C(O)C1=CC=CCCCCCCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
HDAC6 Q9UBN7 2/20 0.37
TSHR P16473 3/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
OAT P04181 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
THRB P10828 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
KMT2A Q03164 1/20 0.35
CTSK P43235 1/20 0.31
SLC6A1 P30531 1/20 0.31
SLC6A13 Q9NSD5 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11801999 1.00 HDAC4 (0.37) HDAC4HDAC2HDAC8HDAC6TSHR
SCHEMBL11801996 1.00 HDAC4 (0.37) HDAC4HDAC2HDAC8HDAC6TSHR
SCHEMBL17962530 0.98 HDAC4 (0.38) HDAC4HDAC2HDAC8HDAC6TSHR
SCHEMBL17962529 0.98 HDAC4 (0.38) HDAC4HDAC2HDAC8HDAC6TSHR
SCHEMBL17962531 0.92 TSHR (0.38) HDAC4HDAC2HDAC8HDAC6TSHR
Cyclohexene SCHEMBL10709788 0.88 TSHR (0.36) TSHRMAPK1HSD17B10OATTDP1
SCHEMBL7838526 0.83 HDAC4 (0.39) HDAC4HDAC2HDAC8HDAC6CTSK
Hydrochloric Acid SCHEMBL2164758 0.83 BLM (0.41) TSHRMAPK1HSD17B10OATTDP1
SCHEMBL607166 0.83
Hydrochloric Acid SCHEMBL3721261 0.81 BLM (0.42) TSHRMAPK1HSD17B10OATTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3932484-A FROM CYCLODODECATRIENE AND CARBON MONOXIDE, COORDINATION CATALYST TEXACO INC. (US) 1976-01-13 US claimed
US-3932484-A FROM CYCLODODECATRIENE AND CARBON MONOXIDE, COORDINATION CATALYST TEXACO INC. (US) 1976-01-13 US disclosed