SCHEMBL11802436

SCHEMBL11802436

CC12CCC(CC1)C(C)(C)C2=O

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 2/20 0.33
MAPK1 P28482 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fenchone SCHEMBL527930 0.86 MEN1 (0.38) MAPTLMNAMEN1ALDH1A1KMT2A
Fenchone SCHEMBL856607 0.86 MEN1 (0.38) MAPTLMNAMEN1ALDH1A1KMT2A
(-)-Fenchone SCHEMBL7997210 0.86 MEN1 (0.38) MAPTLMNAMEN1ALDH1A1KMT2A
Fenchone SCHEMBL15047583 0.86 MEN1 (0.38) MAPTLMNAMEN1ALDH1A1KMT2A
(L)-Fenchone SCHEMBL18221219 0.86 MEN1 (0.38) MAPTLMNAMEN1ALDH1A1KMT2A
(+)-Fenchone SCHEMBL856608 0.86 MEN1 (0.38) MAPTLMNAMEN1ALDH1A1KMT2A
SCHEMBL4140998 0.74 MAPT (0.32) MAPT
SCHEMBL19388309 0.73 TSHR (0.35) MAPTLMNAMEN1ALDH1A1KMT2A
SCHEMBL6623292 0.70 KMT2A (0.41) MAPTLMNAMEN1ALDH1A1KMT2A
SCHEMBL11349549 0.65 MEN1 (0.32) MAPTLMNAMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11331358-B2 Pharmaceutical composition and method of manufacturing SINDERBRAND LAW GROUP, PC 2022-05-17 US disclosed
US-20200246406-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CURE PHARMACEUTICAL HOLDING CORP. (US) 2020-08-06 US disclosed
US-20160000722-A1 DOSAGE FORM FOR CINEOLE MARIA CLEMENTINE MARTIN KLOSTERFRAU VERTRIEBSGESELLSCHAFT MBH (DE) 2016-01-07 US disclosed
CN-105110442-A Treatment agent for removing methanol, normal butanol and isobutanol in amino resin workshop waste water LI HAILAN 2015-12-02 CN disclosed
US-3967629-A Bicyclic fragrance materials and processes therefor INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200246406-A1 PHARMACEUTICAL COMPOSITION AND METHOD OF MANUFACTURING CNR2, CNR1, CYP3A5 MAPT 94/4885LMNA 4008/4885MEN1 3386/4885
US-11331358-B2 Pharmaceutical composition and method of manufacturing CNR2, CNR1, CYP3A5 MAPT 94/4885LMNA 4008/4885MEN1 3386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.