Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11805729 | 0.98 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL222838 | 0.90 | TSHR (0.42) | TSHRTHRBALDH1A1 | |
| SCHEMBL7626091 | 0.88 | TSHR (0.40) | TSHRTHRBALDH1A1 | |
| SCHEMBL13126153 | 0.84 | TSHR (0.45) | TSHRTHRBALDH1A1 | |
| SCHEMBL8914576 | 0.83 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| SCHEMBL28369868 | 0.83 | TSHR (0.40) | TSHRTHRBALDH1A1 | |
| SCHEMBL7628396 | 0.82 | TSHR (0.45) | TSHRTHRBALDH1A1 | |
| SCHEMBL4096632 | 0.82 | TSHR (0.46) | TSHRTHRBALDH1A1 | |
| SCHEMBL11805493 | 0.81 | TSHR (0.34) | TSHR | |
| SCHEMBL1760780 | 0.81 | TSHR (0.41) | TSHRTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935342-A | POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-27 | — | — | US | disclosed |