SCHEMBL11809282

SCHEMBL11809282

Cc1cccc(SSc2cccc(C)c2N)c1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.54
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
CYP3A4 P08684 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
POLB P06746 1/20 0.37
TSHR P16473 2/20 0.36
ACHE P22303 1/20 0.36
ALDH1A1 P00352 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
PIK3CA P42336 1/20 0.36
HTR7 P34969 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31598948 1.00 CD44 (0.54) CD44MEN1MAPTKMT2ANPSR1
SCHEMBL10423683 0.83 CD44 (0.52) CD44MAPTCYP3A4TDP1CYP1A2
SCHEMBL30908373 0.83 CD44 (0.52) CD44MAPTCYP3A4TDP1CYP1A2
SCHEMBL16776729 0.78 CD44 (0.72) CD44CYP3A4TDP1CYP1A2CYP2A6
SCHEMBL106244 0.78
SCHEMBL6734336 0.78 CD44 (0.46) CD44MEN1MAPTKMT2ACYP3A4
SCHEMBL23642743 0.76 CD44 (0.45) CD44CYP3A4TDP1CYP1A2CYP2A6
Ammonia Solution, Strong SCHEMBL1289383 0.75 CD44 (0.68) CD44CYP3A4TDP1CYP1A2CYP2A6
Bromide SCHEMBL10391086 0.75 CD44 (0.68) CD44CYP3A4TDP1CYP1A2CYP2A6
Bromide SCHEMBL28370305 0.75 CD44 (0.68) CD44CYP3A4TDP1CYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3940371-A HYDROLYTIC AND CHEMICAL STABILITY CASE LESLIE C 1976-02-24 US disclosed