Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.91 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11816423 | 0.99 | DRD3 (0.89) | DRD3OPRM1OPRD1ACHE | |
| SCHEMBL11808922 | 0.96 | DRD3 (0.98) | DRD3OPRM1 | |
| SCHEMBL11813871 | 0.95 | DRD3 (1.00) | DRD3OPRM1 | |
| Bromide SCHEMBL11812645 | 0.95 | DRD3 (0.95) | DRD3OPRM1 | |
| SCHEMBL11814580 | 0.95 | DRD3 (1.00) | DRD3OPRM1 | |
| Bromide SCHEMBL11812525 | 0.94 | DRD3 (0.98) | DRD3OPRM1 | |
| Bromide SCHEMBL11818169 | 0.94 | DRD3 (0.98) | DRD3OPRM1 | |
| Ketobemidone SCHEMBL29565806 | 0.86 | DRD3 (0.72) | DRD3OPRM1OPRD1ACHE | |
| Ketobemidone SCHEMBL24574 | 0.86 | DRD3 (0.72) | DRD3OPRM1OPRD1ACHE | |
| Ketobemidone SCHEMBL9706814 | 0.85 | DRD3 (0.70) | DRD3OPRM1OPRD1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3970656-A | ANALGESIC | GOVERNMENT OF THE UNITED STATES (US) | 1976-07-20 | — | — | US | claimed |
| US-3970656-A | ANALGESIC | GOVERNMENT OF THE UNITED STATES (US) | 1976-07-20 | — | — | US | disclosed |