SCHEMBL118096

SCHEMBL118096

O=c1cc(Br)cc[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20299303 0.97
SCHEMBL27189715 0.80 KDM4E (0.40)
SCHEMBL6042142 0.72 NOTUM (0.77)
SCHEMBL9199411 0.70
SCHEMBL6929568 0.70
Bromide SCHEMBL1161612 0.69 NOTUM (0.42)
SCHEMBL23986400 0.68
SCHEMBL13071189 0.68
SCHEMBL165148 0.68
SCHEMBL608199 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 652 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4588918-A1 SYNTHESIS OF (S)-1-(1-(3-CHLOROPHENYL)-2-(DIMETHYLAMINO)ETHYL)- 4-(5-MORPHOLINO-1H-PYRROLO[2,3-B]PYRIDIN-3-YL)PYRIDIN-2(1H)-ONE AGV Discovery (FR) 2025-07-23 EP claimed
EP-4746964-A1 NEW PYRAZOLOPYRIDINE DERIVATIVES F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
EP-4743461-A1 (S)-1-(1- (3-CHLOROPHENYL)-2-(DIMETHYLAMINO) ETHYL)-4-(5 -MORPHOLINO-1H- PYRROLO[2,3-B]PYRIDIN-3-YL) PYRIDIN-2(1H)-ONE,THEIR PREPARATION AND THEIR USE AS ERK KINASE INHIBITORS AGV Discovery (FR) 2026-05-20 EP disclosed
EP-4743460-A1 CRYSTALLINE FORM OF (S)-1-(1- (3-CHLOROPHENYL)-2-(DIMETHYLAMINO) ETHYL)-4- (5 -MORPHOLINO -1H-PYRROLO[2,3-B]PYRIDIN -3-YL)PYRIDIN-2 (1H)-ONE, ITS PREPARATION AND ITS USE AS ERK KINASE INHIBITOR AGV Discovery (FR) 2026-05-20 EP disclosed
WO-2026102309-A1 SELECTIVE RADIOTRACERS AND METHODS OF USE LUTROO IMAGING, LLC (US) 2026-05-15 WO disclosed
CN-122010924-A Aminothiazole heterocyclic compound containing pyridone and synthesis and application thereof 浙江大学 2026-05-12 CN disclosed
EP-3856736-B1 NOVEL COMPOUNDS AS NADPH OXIDASE INHIBITORS CALLIDITAS THERAPEUTICS SUISSE SA (CH) 2026-05-06 EP disclosed
WO-2026090477-A1 HELICASE INHIBITORS AND USES THEREOF KIMIA THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
US-12612407-B2 Imidazo[2,1-f][1,2,4]triazin-4-amine derivatives as TLR7 agonist BEONE MEDICINES I GMBH (CH) 2026-04-28 US disclosed
EP-4720040-A1 SULFONAMIDE COMPOUNDS BENEFICIAL IN NEUROPROTECTIVE TREATMENT Lario Therapeutics Limited (GB) 2026-04-08 EP disclosed
WO-2005090304-A1 ORGANIC COMPOUNDS SPEEDEL EXPERIMENTA AG (CH) 2005-09-29 WO disclosed
WO-2005090305-A1 5-AMINO-4-HYDROXY-7-(1H-INDOLMETHYL)-8-METHYLNONAMIDE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION SPEEDEL EXPERIMENTA AG (CH) 2005-09-29 WO disclosed
EP-0984961-B1 NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ASTRAZENECA AB (SE) 2001-06-20 EP disclosed
US-6143751-A Pyridine derivatives and pharmaceutical compositions containing them ASTRAZENECA UK LIMITED (GB) 2000-11-07 US disclosed
CN-1258296-A Pyridine derivatives and pharmaceutical compositions containing them ASTRA PHARMA PROD (GB) 2000-06-28 CN disclosed
EP-0984961-A1 NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Astra Pharmaceuticals Limited (GB) 2000-03-15 EP disclosed
WO-1998043971-A1 NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ASTRA PHARMACEUTICALS LTD. (GB) 1998-10-08 WO disclosed
US-4052509-A 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE AFFILIATED MEDICAL RESEARCH, INC. (US) 1977-10-04 US disclosed
US-4042699-A 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE AFFILIATED MEDICAL RESEARCH, INC. (US) 1977-08-16 US disclosed
US-3974281-A ANALGESICS, ANTI-PYRETIC AND ANTI-INFLAMMATORY AGENTS AFFILIATED MEDICAL RESEARCH, INC. (US) 1976-08-10 US disclosed