Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | PARL | Q9H300 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11811699 | 1.00 | IDO1 (0.52) | IDO1MAPK1PPARGLMNANFE2L2 | |
| SCHEMBL8664947 | 0.89 | PPARG (0.50) | IDO1MAPK1PPARGOPRM1ALDH1A1 | |
| SCHEMBL8664950 | 0.89 | PPARG (0.50) | IDO1MAPK1PPARGOPRM1ALDH1A1 | |
| SCHEMBL11355618 | 0.83 | IDO1 (0.57) | IDO1PPARGLMNANFE2L2PAM | |
| SCHEMBL11285547 | 0.83 | IDO1 (0.57) | IDO1PPARGLMNANFE2L2PAM | |
| Piperazine SCHEMBL11840225 | 0.83 | PPARG (0.45) | IDO1MAPK1PPARGOPRM1ALDH1A1 | |
| SCHEMBL778798 | 0.80 | IDO1 (0.53) | IDO1PPARGLMNANFE2L2PAM | |
| SCHEMBL14955146 | 0.80 | IDO1 (0.53) | IDO1PPARGLMNANFE2L2PAM | |
| SCHEMBL1169877 | 0.80 | IDO1 (0.53) | IDO1PPARGLMNANFE2L2PAM | |
| SCHEMBL17359707 | 0.80 | IDO1 (0.58) | IDO1PPARGLMNANFE2L2PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083757-B | 2- pi-allyl -1- oxygen -2,3- dihydro -1,2- benzisothiazoles and its preparation method and application | 四川墨凯科技有限公司 | 2018-05-25 | — | — | CN | disclosed |
| CN-106083757-A | 2 pi-allyl 1 oxygen 2,3 dihydro 1,2 benzisothiazoles | 四川墨凯科技有限公司 | 2016-11-09 | — | — | CN | disclosed |
| US-3936429-A | Reactive polymer | FUJI PHOTO FILM CO., LTD. (JA) | 1976-02-03 | — | — | US | disclosed |