Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816011 | 1.00 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MAPTHTTGAA | |
| SCHEMBL11817502 | 0.98 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MAPTHTTGAA | |
| SCHEMBL11812131 | 0.94 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1MAPTHTTGAA | |
| SCHEMBL11634939 | 0.91 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTHTTGAA | |
| SCHEMBL21143307 | 0.91 | HTT (0.55) | SMN1; SMN2ALDH1A1MAPTHTTGAA | |
| SCHEMBL16026649 | 0.91 | HTT (0.55) | SMN1; SMN2ALDH1A1MAPTHTTGAA | |
| SCHEMBL11200026 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1MAPTHTTGAA | |
| SCHEMBL11637394 | 0.86 | KDM4E (0.50) | SMN1; SMN2ALDH1A1MAPTHTTGAA | |
| SCHEMBL11107158 | 0.86 | HTT (0.51) | SMN1; SMN2ALDH1A1MAPTHTTGAA | |
| SCHEMBL14116875 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3946038-A | CHAIN EXTENDERS FOR POLYURETHANES | UNIROYAL, INC. (US) | 1976-03-23 | — | — | US | claimed |
| US-3946038-A | CHAIN EXTENDERS FOR POLYURETHANES | UNIROYAL, INC. (US) | 1976-03-23 | — | — | US | disclosed |