Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559048 | 0.82 | MAPT (0.52) | TP53MEN1KMT2ARXFP1MAPT | |
| SCHEMBL11562150 | 0.79 | CA1 (0.53) | MEN1KMT2ARXFP1MAPTLMNA | |
| SCHEMBL11561285 | 0.79 | RXFP1 (0.46) | TP53MEN1KMT2ARXFP1MAPT | |
| SCHEMBL11560521 | 0.79 | CYP3A4 (0.44) | TP53MEN1KMT2ARXFP1MAPT | |
| SCHEMBL11560561 | 0.78 | MAPT (0.53) | TP53MEN1KMT2ARXFP1MAPT | |
| SCHEMBL11566965 | 0.78 | RXFP1 (0.46) | TP53MEN1KMT2ARXFP1MAPT | |
| SCHEMBL11197862 | 0.77 | KMT2A (0.43) | TP53MEN1KMT2ARXFP1MAPT | |
| SCHEMBL11162712 | 0.77 | KMT2A (0.43) | TP53MEN1KMT2AMAPTLMNA | |
| SCHEMBL11565451 | 0.76 | MEN1 (0.34) | TP53MEN1KMT2ARXFP1MAPT | |
| SCHEMBL11169766 | 0.74 | MAPT (0.52) | TP53MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3972706-A | SUBSTITUTED THIADIAZOL-2-YL-UREAS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |