Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.59 |
| ▸ | HTR2B | P41595 | 11/20 | 0.59 |
| ▸ | HTR2A | P28223 | 6/20 | 0.59 |
| ▸ | HTR6 | P50406 | 9/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819330 | 0.90 | HTR2C (0.67) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL11824656 | 0.90 | HTR2C (0.59) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL11825106 | 0.82 | HTR2C (0.63) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL11824990 | 0.81 | HTR2C (0.59) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL11820144 | 0.80 | HTR2C (0.84) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL11821827 | 0.80 | HTR2C (0.64) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL11826357 | 0.80 | HTR2C (0.67) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL11824911 | 0.79 | HTR2C (0.57) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL11822826 | 0.79 | HTR2C (0.77) | HTR2CHTR2BHTR2AHTR6 | |
| SCHEMBL11818388 | 0.79 | HTR2C (0.54) | HTR2CHTR2BHTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980797-A | Hexahydro-diazepino-indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-09-14 | — | — | US | disclosed |