Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 9/20 | 0.85 |
| ▸ | DRD5 | P21918 | 8/20 | 0.85 |
| ▸ | DRD2 | P14416 | 7/20 | 0.75 |
| ▸ | DRD3 | P35462 | 7/20 | 0.75 |
| ▸ | DRD4 | P21917 | 5/20 | 0.71 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819711 | 1.00 | DRD1 (0.85) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL4317508 | 0.96 | DRD1 (0.79) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL29843474 | 0.96 | DRD1 (0.79) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL29515933 | 0.95 | DRD1 (0.88) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL14340583 | 0.95 | DRD1 (0.88) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL3698679 | 0.93 | DRD1 (0.86) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL10702384 | 0.91 | DRD1 (0.83) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL11815090 | 0.90 | DRD1 (0.70) | DRD1DRD5DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL11819858 | 0.87 | DRD1 (0.74) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL5123364 | 0.86 | DRD1 (0.76) | DRD1DRD5DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3932384-A | CNS DEPRESSANTS, ANALGESICS, SEDATIVES | SHIONOGI & CO., LTD. (JA) | 1976-01-13 | — | — | US | disclosed |