Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27719937 | 1.00 | MAPT (0.56) | MAPTNR5A1PLA2G4BESR1LTA4H | |
| SCHEMBL13303505 | 0.96 | MAPT (0.60) | MAPTNR5A1PLA2G4BLTA4HLMNA | |
| SCHEMBL38661965 | 0.89 | PLA2G4B (0.53) | MAPTNR5A1PLA2G4BESR1LTA4H | |
| SCHEMBL9699866 | 0.89 | PLA2G4B (0.53) | MAPTNR5A1PLA2G4BESR1LTA4H | |
| SCHEMBL9277559 | 0.85 | MAPT (0.61) | MAPTNR5A1PLA2G4BESR1LMNA | |
| SCHEMBL16153093 | 0.84 | MAPT (0.69) | MAPTPLA2G4BLMNAALDH1A1MAPK1 | |
| SCHEMBL1608515 | 0.84 | MAPT (0.69) | MAPTPLA2G4BLMNAALDH1A1MAPK1 | |
| SCHEMBL1608924 | 0.84 | MAPT (0.69) | MAPTPLA2G4BLMNAALDH1A1MAPK1 | |
| Nitrophenolate SCHEMBL10432626 | 0.84 | NR5A1 (0.61) | MAPTNR5A1PLA2G4BESR1LTA4H | |
| SCHEMBL13303357 | 0.84 | MAPT (0.56) | MAPTPLA2G4BESR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3984405-A | PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |