Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319879 | 1.00 | TSHR (0.57) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL31589278 | 0.93 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL19991477 | 0.93 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL31589357 | 0.93 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL9947749 | 0.93 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL36424 | 0.93 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL2458485 | 0.93 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL30338 | 0.93 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL20503431 | 0.93 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL216465 | 0.93 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000218-A | PROCESS FOR PREPARING PARTICULATE POLYURETHANE POLYMERS AND THE POLYMERS DERIVED THEREFROM | UNION CARBIDE CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |