Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830211 | 0.87 | HCAR2 (0.41) | MAOBHCAR2ACEFFAR1FFAR4 | |
| SCHEMBL11837690 | 0.85 | MAOB (0.41) | MAOBHCAR2ACEFFAR1FFAR4 | |
| SCHEMBL11828270 | 0.81 | MAOB (0.42) | MAOBHCAR2FFAR1FFAR4MME | |
| SCHEMBL11824437 | 0.80 | MAOB (0.48) | MAOBHCAR2FFAR1FFAR4CDC7 | |
| SCHEMBL11824134 | 0.80 | MAOB (0.48) | MAOBHCAR2FFAR1FFAR4CDC7 | |
| SCHEMBL11835181 | 0.80 | KDM4E (0.37) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL11827746 | 0.79 | MAOB (0.47) | MAOBHCAR2FFAR1FFAR4CDC7 | |
| SCHEMBL11823591 | 0.79 | MAOB (0.47) | MAOBHCAR2FFAR1FFAR4CDC7 | |
| SCHEMBL11828131 | 0.79 | MAOB (0.50) | MAOBHCAR2FFAR1FFAR4CDC7 | |
| SCHEMBL11826932 | 0.78 | MAOB (0.41) | MAOBHCAR2FFAR1FFAR4MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |