SCHEMBL11831237

SCHEMBL11831237

C=CCC(Cl)CCCCCCCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.37
FAAH O00519 1/20 0.36
DNM1 Q05193 2/20 0.36
ADH1B P00325 1/20 0.35
ADH1C P00326 1/20 0.35
ADH1A P07327 1/20 0.35
ADH4 P08319 1/20 0.35
ADH7 P40394 1/20 0.35
THRB P10828 1/20 0.35
OPRM1 P35372 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
FFAR1 O14842 1/20 0.34
GPR84 Q9NQS5 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2229816 0.91
Methane SCHEMBL27754597 0.89 TSHR (0.39) TSHRALDH1A1DNM1
Bromide SCHEMBL27728857 0.89 TSHR (0.39) TSHRALDH1A1DNM1
Fluoride SCHEMBL29210793 0.89 TSHR (0.39) TSHRALDH1A1DNM1
Hydrochloric Acid SCHEMBL27886331 0.89 TSHR (0.39) TSHRALDH1A1DNM1
Methylene Chloride SCHEMBL28228656 0.87 TSHR (0.37) TSHRALDH1A1DNM1
Cyclohexane SCHEMBL28501260 0.85 TSHR (0.36) TSHRALDH1A1DNM1
Benzene SCHEMBL28152757 0.85 TSHR (0.36) TSHRALDH1A1DNM1
SCHEMBL8925265 0.81
SCHEMBL28806421 0.81 TSHR (0.67) TSHRALDH1A1LMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3931238-A BETAINE CATALYST CONTINENTAL OIL COMPANY (US) 1976-01-06 US disclosed