Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 13/20 | 0.48 |
| ▸ | TP53 | P04637 | 9/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984879 | 0.84 | MAPT (0.52) | MYCSERPINE1MAPTTP53THRB | |
| SCHEMBL13240626 | 0.82 | MAPT (0.46) | MYCSERPINE1MAPTTP53THRB | |
| SCHEMBL2992714 | 0.80 | MAPT (0.47) | SERPINE1MAPTTP53THRBLMNA | |
| SCHEMBL11696697 | 0.80 | MAPT (0.57) | MYCSERPINE1MAPTTP53THRB | |
| SCHEMBL11834489 | 0.80 | SERPINE1 (0.57) | MYCSERPINE1MAPTTP53THRB | |
| SCHEMBL11841289 | 0.79 | MAPT (0.58) | MYCSERPINE1MAPTTP53THRB | |
| SCHEMBL2991459 | 0.78 | MAPT (0.53) | MAPTTP53THRBLMNAPKM | |
| SCHEMBL2988545 | 0.78 | MAPT (0.47) | MAPTTP53THRBLMNAKDM4E | |
| SCHEMBL2999476 | 0.77 | MAPT (0.42) | SERPINE1MAPTTP53THRBLMNA | |
| SCHEMBL12091683 | 0.76 | KDM4E (0.49) | MYCSERPINE1MAPTTP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3931407-A | ANTIINFLAMMATORY, ANALGESIC | AMERICAN HOECHST CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |