Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11833065 | 0.82 | CFTR (0.46) | CFTRGOPCMAPTLMNAKMT2A | |
| Acetic Acid SCHEMBL9529245 | 0.79 | CFTR (0.45) | CFTRGOPCMAPTLMNAKMT2A | |
| SCHEMBL31202620 | 0.76 | PDK2 (0.53) | CFTRGOPCMAPTLMNAKMT2A | |
| SCHEMBL10554281 | 0.76 | PDK2 (0.53) | CFTRGOPCMAPTLMNAKMT2A | |
| SCHEMBL11241768 | 0.75 | CFTR (0.46) | CFTRGOPCMAPTLMNAKMT2A | |
| SCHEMBL10550632 | 0.69 | PDK2 (0.41) | CFTRGOPCMAPTLMNAKMT2A | |
| SCHEMBL7697104 | 0.69 | CFTR (0.50) | CFTRGOPCMAPTLMNAKMT2A | |
| SCHEMBL3505329 | 0.68 | CFTR (0.53) | CFTRGOPCMAPTLMNAKMT2A | |
| SCHEMBL31084368 | 0.68 | CFTR (0.53) | CFTRGOPCMAPTLMNAKMT2A | |
| SCHEMBL13109881 | 0.67 | CFTR (0.48) | CFTRGOPCMAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959269-A | TRANQUILIZERS, SEDATIVES | SANDOZ, INC. (US) | 1976-05-25 | — | — | US | disclosed |