Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.67 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.67 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.67 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11837225 | 0.94 | AKR1C3 (0.63) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11837722 | 0.94 | AKR1C3 (0.62) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11831599 | 0.94 | AKR1C3 (0.77) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11838831 | 0.92 | AKR1C3 (0.77) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11842519 | 0.91 | AKR1C3 (0.62) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11840314 | 0.90 | AKR1C3 (0.84) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11848743 | 0.89 | AKR1C3 (0.58) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11842313 | 0.87 | AKR1C3 (0.54) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11847372 | 0.84 | AKR1C3 (0.64) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 | |
| SCHEMBL11836677 | 0.84 | AKR1C3 (0.52) | AKR1C3AKR1C2PTGS1AKR1C4AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948939-A | 9-Acyl-1,2,3,4-tetrahydrocarbazole-3 and 4-carboxylic acids | STERLING DRUG INC. (US) | 1976-04-06 | — | — | US | disclosed |