Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11830375 | 0.88 | KDM4E (0.46) | KDM4ETSHRMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11837862 | 0.87 | KDM4E (0.45) | KDM4ETSHRMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11832562 | 0.85 | KDM4E (0.55) | KDM4ETSHRMEN1KMT2AMAPT | |
| SCHEMBL11835066 | 0.77 | KDM4E (0.65) | KDM4ETSHRMEN1KMT2AMAPT | |
| SCHEMBL11832922 | 0.77 | KDM4E (0.72) | KDM4ETSHRMEN1KMT2AMAPT | |
| SCHEMBL11830991 | 0.77 | KDM4E (0.47) | KDM4ETSHRMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11837543 | 0.76 | KDM4E (0.70) | KDM4ETSHRMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11834681 | 0.76 | KDM4E (0.47) | KDM4ETSHRMEN1KMT2AMAPT | |
| SCHEMBL11842018 | 0.75 | KDM4E (0.69) | KDM4ETSHRMEN1KMT2AMAPT | |
| SCHEMBL11846471 | 0.75 | KMT2A (0.50) | KDM4ETSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |