Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | PPARD | Q03181 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSPO | P30536 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11841325 | 0.99 | TSHR (0.61) | TSHRHTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL1332277 | 0.93 | TSHR (0.64) | TSHRHTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL11839319 | 0.85 | KMT2A (0.59) | TSHRHTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL1332126 | 0.84 | TSHR (0.54) | TSHRHTR2AHTR2CHTR2BPTGDR2 | |
| Hydrochloric Acid SCHEMBL11841321 | 0.84 | KMT2A (0.58) | TSHRHTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL1332012 | 0.83 | TSHR (0.53) | TSHRHTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL1538036 | 0.83 | KMT2A (0.69) | TSHRHTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL1332765 | 0.82 | TSHR (0.55) | TSHRHTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL4179059 | 0.82 | TSHR (0.61) | TSHRHTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL28483915 | 0.82 | KMT2A (0.67) | TSHRHTR2AHTR2CHTR2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992543-A | (Pyridyl-3)-methyl 2-(p-chlorophenoxy-phenoxy) propionate and use as a hypolipemising drug | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 1976-11-16 | — | — | US | disclosed |